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Brain and nerve health; Healthy aging; Immune support; Exercise recovery; Balanced inflammatory response
Adults who want focused omega-3 derivatives for everyday recovery after activity or those seeking convenient daily support for balanced inflammatory signals.
Take 1 gelcap once daily, preferably with a meal to enhance tolerance and absorption of fat-soluble components.
Gluten Free. Contains: Fish and shellfish (anchovy, sardine, squid, herring, mackerel).
DHA incorporates into neuronal and immune cell membranes, where it is converted into specialized pro-resolving mediators and supports fluidity and signaling balance.
Caution: Fish-derived oils may cause fishy aftertaste or mild digestive upset, so taking with food can improve tolerance; those with fish or shellfish allergies should avoid it.
EPA integrates into cell membranes and is converted into signaling compounds, including precursors to resolvins, that may support a balanced inflammatory response.
Caution: May increase bleeding tendency at high intakes, especially when combined with blood-thinning agents, so monitor for easy bruising.
18-HEPE is a direct precursor to E-series resolvins that may help signal the resolution phase of the inflammatory process.
Caution: Concentrations are low, but individuals sensitive to fish products should be cautious due to the marine source.
17-HDHA is a precursor to D-series resolvins and protectins that help the body signal completion of the inflammatory response.
Caution: Derived from fish oil; people with fish or shellfish allergies should avoid it.
14-HDHA serves as a DHA-derived intermediate that may promote resolution signaling pathways in tissues.
Caution: As a marine oil derivative, it may cause mild gastrointestinal upset in sensitive individuals, especially on an empty stomach.
DHA and EPA provide foundational omega-3s that incorporate into cell membranes and supply substrates for pro-resolving mediator pathways. 18-HEPE, 17-HDHA, and 14-HDHA act as direct precursors that the body can convert into resolvins and protectins, complementing the parent omega-3s by offering ready-to-use resolution intermediates.
Label Warning: Use only if bottle is sealed. If pregnant, consult your health-care practitioner before using this product.
Who should be cautious: People with fish or shellfish allergies may need to avoid this product. Those on blood-thinning medications or with bleeding concerns may need caution with omega-3 fish oil; discuss with a healthcare provider before use.
Storage: Store tightly sealed in a cool, dry place.
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Since Vitamin D is fat-soluble, taking it with Omega-3 may enhance absorption and help maintain bone, mood, and metabolic balance.
AI generated. Not medical advice.
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Pro-Resolving mediators (PRMs) are the end products of the body’s metabolism of EPA and DHA. Thorne’s Pro-Resolving Mediators supplement includes the precursors the body needs to create pro-resolving mediators – two pre-resolving mediators 17-HDHA and 14-HDHA from DHA and one pre-resolving mediator 18-HEPE from EPA, as well as their parents EPA and DHA, to deliver a one-two punch in support of a balanced inflammatory response. A balanced inflammatory response helps bring the body back into homeostasis after an injury or other insult – essentially helping to “resolve” the problem. In fact, groups of PRMs produced in the body are called resolvins and protectins – basically members of the body’s “cleanup crew.”
Benefits of Thorne’s Pro-Resolving Mediators:
Take 1 gelcap daily or as recommended by your health-care practitioner.
Highly refined concentrated marine oil, gelatin (bovine), glycerin (vegetable source) and purified water gelcap, mixed tocopherols.
Contains ingredients derived from fish and/or shellfish (fish oil = anchovy, sardine, squid, herring, mackerel).
Manufactured in the USA using U.S.& imported ingredients.
Use only if bottle is sealed. Store tightly sealed in a cool, dry place.
If pregnant, consult your health-care practitioner before using this product.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: One Gelcap | ||
| Amount Per Serving | %Daily Value | |
| Calories | 10 | |
| Total Fat | 1 g | 1%* |
| Cholesterol | 5 mg | 2%* |
| Marine Lipid Concentrate (from Fish Oil) [providing 300 mcg of Pro-Resolving Mediators including 18-hydroxyeicosapentaenoic acid (18-HEPE), 17-hydroxyeicosapentaenoic acid (17-HDHA), and 14-hydroxyeicosapentaenoic acid (14-HDHA)] | 650 mg | ** |
| Total Omega-3 Fatty Acids (from Fish Oil) | 500 mg | ** |
| DHA (Docosahexaenoic Acid) | 250 mg | ** |
| EPA (Eicosapentaenoic Acid) | 160 mg | ** |
| *Percent Daily Values are based on a 2,000 calorie diet. **Daily Value (DV) not established. | ||
